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Clinical Study 2

Corroborating Clinical Confirmation:
Patients with Joint Discomfort

Elderly woman suffering from pain in hand, arthritis old person and senior woman female suffering from pain at home

This second randomized, double-blind, placebo-controlled study explored how a 250mg dose of TamaFlex affected subjects with induced joint discomfort. Sixty (60) subjects (male and female 40-70 years old) were chosen and randomized for the baseline visit and three follow-up visits on days 5, 28, and 56, where the WOMAC self-assessment test was used as the primary efficacy measure.

Findings from Clinical Study 2


Results found that, by day 5, the TamaFlex group started showing:


Improvement in comfort


Improvement in walking distance covered


Improvement in stiffness


Improvement in stair climbing time


Improvement in physical activity


Improvement in knee flexion scores

Of note with this study is that objective BioMarkers were tested and reviewed. Researchers also found significant reductions in TNF-α, hsCRP, and IL-6 levels in TamaFlex subjects, indicating the support of healthy inflammation systemically and specifically of the knee . TamaFlex also significantly reduced Matrix metalloproteinase-3 (MMP-3) activity, the compound that is involved with the breakdown of connective tissue. No serious adverse events were observed.

More TamaFlex Clinical Studies


Clinical Study 1

A 90-Day Study with Healthy Participants


Clinical Study 3

Confirms 5-day Joint Health Benefits: Patients With Mild Discomfort

* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease

† Refers to normal inflammation from exercise or everyday activities.

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