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Human Studies

Clinical studies show TamaFlex® has significant benefits

Human clinical studies have shown benefits with healthy subjects and subjects with joint discomfort caused by physical activity.

TamaFlex is clinically validated in three human studies that tested TamaFlex® against a placebo. The researchers examined the following:

  • Performance – walking speed and distance, going up and down stairs, sitting to standing, and how far the knee joint can bend!
  • Comfort & Function – how participants' joints felt.
  • Objective Measurements – taking blood samples that confirmed healthy inflammation levels and protection of cartilage and joint fluids.

The groups that took TamaFlex® showed significant improvements in mobility while the placebo group did not. Participants taking TamaFlex® found that they could walk farther and handle stairs better with increased strength and endurance. They also felt comfortable knowing that they were taking a food-based, animal-free, natural supplement instead of artificial supplements.

Clinical Study 1

In a randomized, double-blinded trial, 90 healthy adults took TamaFlex® or placebo twice daily for 90 days. The study showed:

TamaFlex® effectively improved joint health by reducing joint discomfort and stiffness, leading to improved physical function in healthy subjects with joint issues caused by physical activity.

TamaFlex® effectively improved joint health by reducing joint discomfort and stiffness, leading to improved physical function in healthy subjects with joint issues caused by physical activity.

TamaFlex® 250 mg and 400 mg significantly increased distance walked (6MWD), reduced both Stair Climb Time and Pain Scores measured by the Visual Analog Scale and VAS, WOMAC discomfort, stiffness, and physical function scales when compared to placebo.

TamaFlex® significantly improved knee flexion – the amount the joint can move and flex - measured using goniometer and physician global assessment score.

TamaFlex® provided significant benefits as early as 14 days of supplementation.

No serious adverse events were observed with TamaFlex®.

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Results - Clinical Study 1

All clinical human trials supporting joint health were performed with healthy subjects with joint discomfort caused by physical activity. In a randomized, double-blinded trial, 90 healthy adults took TamaFlex® or placebo twice daily for 90 days. The study showed:

Assessment of 6-Minute Walk Test

Assessment-of-6-Minute-Walk-Test copy

23-38% improvement!

Assessment of Stair Climb Test

Assessment of Stair Climb Test

20-23% improvement!

Assessment of VAS Score
(measure of discomfort)

Assessment of VAS Score

32-46% improvement!

Assessment of Primary Knee Flexion

Assessment of Primary Knee Flexion

3.43° – 5.3° improvement
in articulation!

Clinical Study 2

New TamaFlex® Study Shows it Starts Working in 5 Days

This second human clinical trial, a randomized, double-blind, placebo-controlled study was to assess the efficacy of TamaFlex® in joint discomfort and improvement in the musculoskeletal function of participants with existing knee discomfort. Improvements in the functional scores, pre-markers of healthy inflammatory levels, and measures of cartilage integrity were secondary efficacy measures. The study showed:

TamaFlex® effectively improved joint health by reducing joint discomfort and stiffness, leading to improved physical function in subjects with joint issues caused by physical activity.

Importantly, TamaFlex® provided significant benefits as early as 5 days of supplementation.

TamaFlex® 250 mg and 300 mg of TamaFlex® Plus significantly increased distance walked (6MWD), reduced both Stair Climb Time and Pain Scores measured by the Visual Analog Scale and VAS, WOMAC discomfort, stiffness, and physical function scales when compared to placebo.

TamaFlex® helped to support healthy inflammation levels and supported cartilage integrity in the participants as measured in biomarkers – an objective measurement.

TamaFlex® significantly improved knee flexion – the amount the joint can move and flex - measured using goniometer and physician global assessment score.

No significant adverse events were observed with TamaFlex®, demonstrating that is well tolerated for daily use.

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Results - Clinical Study 2

All clinical human trials supporting joint health were performed with subjects with existing knee discomfort. In a randomized, double-blinded trial, 60 adults took TamaFlex® or placebo twice daily for 56 days. The study showed improvement in 5 days:

 

Assessment of 6-Minute Walk Test

Tamaflex second study graphs (1).xlsx

Assessment of VAS Score
(measure of discomfort)

Tamaflex second study graphs (1).xlsx

Assessment of Stair Climb Test

Tamaflex second study graphs (1).xlsx

Assessment of Primary Knee Flexion

Tamaflex second study graphs (1).xlsx

Scientific Resources 

Published research in laboratory and human studies supports the efficacy and safety of TamaFlex®. Explore the resources that NXT-USA has to support your finished product needs. Sales sheet, white papers, safety and toxicological evaluations are all available upon request.

Hogne-Vik PHD - An older caucasian man smiling. He is wearing a black jacket and a white collared shirt.

"More effective than glucosamine/chondroitin, because few users report real relief, whereas TamaFlex® shows significant relief compared to placebo."

Hogne Vik
MD, PhD

virolog-coducting-experiment-course-coronavirus-pandemic-with-micropipette-chemist-modern-laboratory-doing-research-using-dispenser-during-global-epidemic-with-covid-19

Learn about TamaFlex® safety

TamaFlex® is a unique, standardized blend of Tamarind Seed and Full-Spectrum Turmeric, two research-backed and well-recognized joint health ingredients with a strong history of traditional use.