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Human Studies


TamaFlex is clinically validated in three human studies that tested TamaFlex against a placebo.

Improved Comfort: Physician assessment shows significant improvements.*

Preserved Structure: Bio-assays show improved protection against cartilage and synovial fluid degradation, supporting important connective tissues.*

Increased Activity:The net result? Increased aerobic activity with walking distance, speed, stair-climbing, and lower body strength.†


A 90-Day Study with Healthy Participants

Corroborating Clinical Confirmation: Patients with Joint Discomfort

Confirms 5-day Joint Health Benefits: Patients With Mild Discomfort

Scientific Resources 

Published research in laboratory and human studies supports the efficacy and safety of TamaFlex®. Explore the resources that NXT-USA has to support your finished product needs. Sales sheet, white papers, safety and toxicological evaluations are all available upon request.

Hogne-Vik PHD - An older caucasian man smiling. He is wearing a black jacket and a white collared shirt.

"More effective than glucosamine/chondroitin, because few users report real relief, whereas TamaFlex® shows significant relief compared to placebo."

Hogne Vik


Learn about TamaFlex® safety

TamaFlex® is a unique, standardized blend of Tamarind Seed and Full-Spectrum Turmeric, two research-backed and well-recognized joint health ingredients with a strong history of traditional use.

* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease

† Refers to normal inflammation from exercise or everyday activities.

Kare SK, Vinay V, Maresz K, Prisk V, Vik H. Tamarindus indica seed extract-based botanical compositions alleviate knee pain and improve joint function in mild-to-moderate osteoarthritis: a randomized, double-blind, placebo-controlled clinical study. Evid Based Complement Alternat Med. 2022 Jan 19;2022:2226139. doi: 10.1155/2022/2226139. PMID: 35096104; PMCID: PMC8791717.

Rao PS, Ramanjaneyulu YS, Prisk VR, Schurgers LJ. A Combination of Tamarindus indica seeds and Curcuma longa Rhizome extracts improves knee joint function and alleviates pain in non-arthritic adults following physical activity. Int J Med Sci. 2019 Jun 2;16(6):845-853. doi: 10.7150/ijms.32505. PMID:31337958; PMCID: PMC6643110.

Prasad N., Vinay V., and Srivastava A. Efficacy of a Proprietary Combination of Tamarindus indica Seeds and Curcuma longa Rhizome Extracts in Osteoarthritis: A Clinical Investigation. Food & Nutrition Research, vol. 67, 2023 June 20, doi: 10.29219/fnr.v67.9268.